A case report on Acquired Ichthyosis and Autoimmune Hepatitis

Document Type : Case Report


1 Ross University School of Medicine, Miramar, Florida, USA

2 Universidad Mayor de San Simón, Cochabamba, Bolivia

3 Dr. Kiran C Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, Florida, USA

4 UMC Free Clinic, Miami Gardens, Florida, USA

5 College of Medicine, University of Science, Arts and Technology, Olveston, P.O. Box 506, British West Indies

6 College of Biomedical Sciences, Larkin University, Miami, Florida, USA



Background and Objectives: Juvenile autoimmune hepatitis is an inflammatory immune-mediated liver disease that affects infants to adolescents. Clinical presentation of AIH may resemble other hepatic diseases such as viral or toxic hepatitis and Wilson disease, presenting with fatigue, nausea, vomiting, jaundice, fever, and pruritus.
Case Presentation: A 16-year-old male with a history of congenital ichthyosis, xerosis cutis, mild intermittent asthma and environmental allergic rhinitis presented to the clinic with upper respiratory symptoms. The patient appeared jaundiced, which prompted referral for acute evaluation leading to a diagnosis of autoimmune hepatitis and inflammatory bowel disease. Discussion: Juvenile autoimmune hepatitis is a rare and quite serious inflammatory liver disorder affecting infants to adolescents. Due to its resemble with many other liver disease, differential diagnosis is bit challenging. Overall, our patient's prognosis appears to be positive.


Main Subjects

Articles in Press, Corrected Proof
Available Online from 22 October 2023
  • Receive Date: 02 October 2023
  • Revise Date: 16 October 2023
  • Accept Date: 22 October 2023